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Ultimate Grilled Cheese Sandwich

A grilled cheese sandwich with prosciutto, basil, asiago cheese, tomato, and red pepper.

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Why it works: Olive and tomato are a kitchen classic. They rank in the top 1% of all ingredient pairs, and cooks put them together in 15,539 recipes. Both carry 3-hexenal, which smells apple, fruity. The science ↓

Ultimate Grilled Cheese Sandwich

Oven400°F
Timeabout 9 minutes in the skillet and oven

Ingredients

Directions

Prepare the sandwiches

  1. Preheat oven to 400°F.

  2. Lightly butter 1 side of each bread slice.

  3. Place 2 bread slices, buttered side down, on work surface.

  4. Top each with 2 prosciutto slices, then 4 basil leaves, then 4 cheese slices.

  5. Sprinkle with salt and crushed red pepper.

  6. Top with remaining 2 bread slices, buttered side up.

Cook and bake

  1. Heat olive oil in heavy large ovenproof skillet over medium-high heat.

  2. Add sandwiches to skillet and cook until golden on bottom, about 4 minutes.

  3. Turn sandwiches over; transfer skillet to oven and bake until golden and cheese melts, about 5 minutes.

  4. Remove from oven.

Add tomato and serve

  1. Carefully lift off top bread slices from sandwiches and insert 3 tomato slices into each, then cover with bread tops and serve.

Nutrition, whole recipe (rough)

998Calories
32 gProtein
43 gFat
120 gCarbs
What these numbers assume: 9 portions
IngredientPortion assumedkcal
Flour1 cup (125g) all-purpose455
Olive Oil1 tbsp (14g)119
Cheese1 oz (28g) cheddar113
Butter1 tbsp (14g)102
Sourdough1 slice (36g)93
Mozzarella Cheese1 oz (28g)85
Tomato1 medium (123g)22
Chili1 tsp (2.7g)8
Basil5 leaves fresh (2.5g)1

One typical portion per ingredient; the recipe's quantities are not counted. A rough guide only, not for medical or dietary planning.

Recipe from the Recipes Wiki (Fandom).

Steps grouped into stages for easier reading; the method is the source's own.

Explore the science

The flavor team

The pairs that carry this dish. Each one is judged two ways: how much their aromas overlap, and how often cooks already put them together.

  1. Olive + tomatotop 1% of all pairs
    Smell alikemoderate
    Cooked together15,539 recipes

    Shared aroma: 3-hexenal (apple, fruity).

  2. Basil + tomatotop 1% of all pairs
    Smell alikemoderate
    Cooked together3,979 recipes

    Shared aroma: 3-hexenal (apple, fruity).

  3. Basil + olivetop 3% of all pairs
    Smell alikemoderate
    Cooked together5,063 recipes

    Shared aroma: 3-hexenal (apple, fruity).

  4. Basil + peppertop 4% of all pairs
    Smell alikestrong
    Cooked together5,294 recipes

    Shared aroma: methyl cinnamate (strawberry).

  5. Butter + breadtop 7% of all pairs
    Smell alikemoderate
    Cooked together27,232 recipes

    Shared aroma: delta-decalactone (sweet, creamy).

Ranks compare each pair with 20,000 random ingredient pairs on CompKitchen. How we score pairs

What each ingredient does

Sourdough bread
Provides a sturdy structure that crisps and browns when pan-fried and baked.
Asiago cheese
Melts to bind the sandwich together and adds rich, savory flavor.
Prosciutto
Adds salty, savory depth that complements the melted cheese.
Heirloom tomato
Adds juicy moisture and acidity that balances the rich cheese and bread.
Butter
Promotes browning and golden color on the bread surface.

The step that matters

Carefully lift off top bread slices. Tomato slices are inserted after baking, so lifting the bread gently keeps the hot, melted cheese filling intact and prevents the sandwich from tearing or sliding apart.

Swap the basil

How well each one fits the dish's main ingredients (butter, bread, prosciutto, cheese, pepper, olive, tomato):

  1. Thymefits about as well
  2. Garlicfits about as well
  3. Basilthe original
  4. Parsleyfits about as well

Fit is the average pairing score against butter, bread, prosciutto, cheese, pepper, olive, tomato. Candidates are from the same food group and used in at least 100 recipes.

“What each ingredient does” and “The step that matters” were written by Claude from this recipe’s own method and reviewed in samples by CompKitchen.

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